黑色素瘤相關(guān)抗原5抗體
規(guī)格：1mg/1ml
英文名： MAGEA5
別名： Cancer/testis antigen 1.5; Cancer/testis antigen family 1 member 5; CT1.5; MAGE 5 antigen; MAGE 5a antigen; MAGE 5b antigen; MAGE5; MAGEA4; Melanoma antigen family A 5; Melanoma associated antigen 5;
分子量： 13kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from hu MAGEA5
交叉反應：Human,
細胞定位：
黑色素瘤相關(guān)抗原5抗體產(chǎn)品介紹：background: MAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively 黑色素瘤相關(guān)抗原5抗體interpreted to be a pseudogene. Function: Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines. Tissue Specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Similarity: Contains 1 MAGE domain. Gene黑色素瘤相關(guān)抗原5抗體 ID: 4104 Database links: Entrez Gene: 4104 Human Entrez Gene: 100533997 Human Omim: 300340 Human SwissProt: P43359 Human Unigene: 668021 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
黑色素瘤相關(guān)抗原5抗體產(chǎn)品應用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領域：腫瘤 細胞生物 **學 腫瘤細胞生物標志物
儲存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
外觀： Lyophilized or Liquid