鈣離子通道阻端耐藥蛋白CCBR1抗體
規(guī)格：1mg/1ml
英文名： CCBR1
別名： Amino acid transport system xc xCT antibody; Amino acid transport system xc- antibody Calcium channel blocker resistance protein CCBR1; Calcium channel blocker resistance protein CCBR1 antibody; CCBR1
分子量： 55kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human xCT/CCBR
交叉反應(yīng)：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
細(xì)胞定位：
鈣離子通道阻端耐藥蛋白CCBR1抗體產(chǎn)品介紹：background: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq,鈣離子通道阻端耐藥蛋白CCBR1抗體 Sep 2011]. Function: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. Subunit: Disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc鈣離子通道阻端耐藥蛋白CCBR1抗體 (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family. Database links: UniProtKB/Swiss-Prot: Q9UPY5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)鈣離子通道阻端耐藥蛋白CCBR1抗體品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 **學(xué) 通道蛋白
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Rabbit
外觀： Lyophilized or Liquid