環(huán)指蛋白189抗體
規(guī)格：1mg/1ml
英文名： RING finger protein 189
別名： CARP-2; CARP2; Caspase regulator CARP2; Caspases 8 and 10 associated RING finger protein 2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin protein ligase rififylin; E3 ubiquitin-pro
分子量： 40kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RING fin
交叉反應(yīng)：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
細(xì)胞定位：細(xì)胞漿 細(xì)胞膜
環(huán)指蛋白189抗體產(chǎn)品介紹：background: Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates. Subunit: Binds CASP8 and CASP10. Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Tissue Specificity: Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. Post-translational modifications: Rapidly degraded after stimulation with TNFSF10, probably by caspases. Auto-ubiquitinated (in vitro). Palmitoylated. Similarity: Contains 1 FYVE-type zinc finger. Contains 環(huán)指蛋白189抗體1 RING-type zinc finger. Contains 2 SAP domains. Gene ID: 117584 Database links: Entrez Gene: 530263 Cow Entrez Gene: 117584 Human Entrez Gene: 67338 Mouse Entrez Gene: 282844 Rat Omim: 609735 Human SwissProt: Q8WZ73 Human SwissProt: Q6ZQM0 環(huán)指蛋白189抗體Mouse SwissProt: Q8CIN9 Rat Unigene: 13680 Human Unigene: 341608 Mouse Unigene: 159718 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)環(huán)指蛋白189抗體品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Rabbit
外觀： Lyophilized or Liquid