卷曲螺旋結(jié)構(gòu)域蛋白17抗體
規(guī)格：1mg/1ml
英文名： CCDC17
別名： CCD17_HUMAN; CCDC17; Coiled coil domain containing 17; Coiled-coil domain-containing protein 17; RP23-233B9.8; RP4-697E16.4.
分子量： 68kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCDC17
交叉反應(yīng)：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
細(xì)胞定位：
卷曲螺旋結(jié)構(gòu)域蛋白17抗體產(chǎn)品介紹：background: CCDC17, also known as FLJ17921 or RP4-697E16.4, is a 622 amino acid protein expressed as four isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH 卷曲螺旋結(jié)構(gòu)域蛋白17抗體gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant卷曲螺旋結(jié)構(gòu)域蛋白17抗體 melanoma and multiple myeloma. Database links: UniProtKB/Swiss-Prot: Q96LX7.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)卷曲螺旋結(jié)構(gòu)域蛋白17抗體品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 **學(xué)
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
外觀： Lyophilized or Liquid