卷曲螺旋結(jié)構(gòu)域蛋白51抗體
規(guī)格：1mg/1ml
英文名： CCDC51
別名： CCD51_HUMAN; CCDC51; Coiled-coil domain-containing protein 51; FLJ12436; RGD1311466; AI551049; 5730568A12Rik.
分子量： 45kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCDC51
交叉反應(yīng)：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
細(xì)胞定位：細(xì)胞膜
卷曲螺旋結(jié)構(gòu)域蛋白51抗體產(chǎn)品介紹：background: The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC51 (coiled-coil domain containing 51) is a 411 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding CCDC51 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, 卷曲螺旋結(jié)構(gòu)域蛋白51抗體cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Database links: UniProtKB/Swiss-Prot: Q96ER9.2 Entrez Gene: 卷曲螺旋結(jié)構(gòu)域蛋白51抗體79714 Human Entrez Gene: 66658 Mouse Entrez Gene: 316008 Rat SwissProt: Q96ER9 Human SwissProt: Q3URS9 Mouse SwissProt: Q5PPN7 Rat Unigene: 187657 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卷曲螺旋結(jié)構(gòu)域蛋白51抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 **學(xué)
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
外觀： Lyophilized or Liquid